Tilmicosin                

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bulletChemical Structure
bulletChemical Formula
C46H80N2O13
bulletMolecular Weight:
869.15
bulletCas No.:
108050-54-0
bulletChemical Name

Tilmicosin (IUPAC name): (10E, 12E)-(3R,4S,5S,6R,8R,14R,15R)-14-(6-deoxy-2,3-di-O-methyl-b-d-allo-hexopyranosyoxymethyl)-5-(3,6-dideoxy-3-dimethylamino-b-d-gluco-hexapyranosyloxy)-6-[2-(cis-3,5-dimethyl-piperidino)ethyl]-3-hydroxy-4,8,12-trimethyl-9-oxoheptadeca-10,12-dien-15-olide

Chemical Abstracts Services Name: tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-20-deoxy-20-(3,5-dimethyl-1-piperidinyl)-(20(cis: trans))

bulletSynonyms
20-Deoxy-20-(3,5-dimethylpiperidin-1-yl)-desmycosin, Tilmicosin Phosphate
bulletCompliance
USP24  
bulletDescription

 A white or off-white powder, Freely soluble (1500 mg/L or greater) in organic solvents (hexane, acetone, acetonitrile, chloroform, dichloromethane, ethyl acetate, methanol, tetrahydrofuran); water solubility is temperature and pH dependent, but is 566 mg/mL at pH 7 and 25°C.

bulletIndications
Tilmicosin is a macrolide antibiotic developed for veterinary use. It is recommended for treatment and prevention of pneumonia in cattle, sheep and pigs, associated with Pasteurella haemolytica, P. multocida, Actinobacillus pleuropneumoniae, mycoplasma species and other microorganisms found sensitive to this compound. It is an antibiotic medicine with great antibiotic effect and broad antibiotic spectrum . Not show resistance and cross-resistance with other antibiotic often used in clinic. Mainly used in the Pleuropneumonia and the infection caused by Pasteurellaceae , Pasteurella and mycoplasma
bulletSpecification
Tilmicosin consists of 82-88% cis isomer and 12-18% trans isomer, as determined by liquid chromatographic assay.(Assay:Min. 85%)
bulletDosage & Administration
formulations of tilmicosin include an injectable for use in cattle and sheep (30% Injection) and premix formulations for swine (4%, 10% & 20% Premix). The recommended dose of the injectable formulation in both cattle and sheep is a single subcutaneous (SC) injection of 10 mg/kg BW. Recommended dose for swine in feed is 200-400 mg/kg of feed for 10 to 21 days, equivalent to 8-20 mg/kg BW per day.
bulletPacking:
 1 Kg or 5 Kgs in one Aluminum Tin; 10 Kgs per carton.
bulletStorage
Protected from light , stored hermetically and in a dry place.
bulletShelf Life
2 years.
bulletRemarks
In need of further information, please kindly us at: biok@vetamo.com or davidvan2000@hotmail.com or call our direct phone: 0086 133 5582 2008

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